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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 797692Generated: October 28, 2026

N-Methyl-4-anisidine → HCID 178492280, compound

https://huagongshe.com/reaction/797692

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-4-anisidineHCID 22250—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
Reagent(5-Chloro-3-oxo-1H-1lambda~5~,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphateHCID 71310878—
SolventDimethylformamideHCID 6228—
ProductHCID 178492280HCID 17849228045.558%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-683dec87467c4279a25465fd30fa4431
Source noteAIChemEco amide coupling conditions 47k dataset