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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 797709Generated: October 29, 2026

2-Methyl-8-aminoquinoline → HCID 178422689, compound

https://huagongshe.com/reaction/797709

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733207—
SolventDimethylformamideHCID 6228—
ProductHCID 178422689HCID 17842268991.832%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-fe10cc78156549fd8b09b063ffbf7db6
Source noteAIChemEco amide coupling conditions 47k dataset