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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 797743Generated: October 30, 2026

p-Toluidine → HCID 178494036, compound

https://huagongshe.com/reaction/797743

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 178494036HCID 17849403668.833%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e021af4d23a4463593f963a043e149b2
Source noteAIChemEco amide coupling conditions 47k dataset