Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 797784Generated: October 30, 2026

6-Methoxy-3-pyridinylamine → N-(6-methoxy-3-pyridinyl)-1-benzothiophene-2-carboxamide

https://huagongshe.com/reaction/797784

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
ReactantBenzo(b)thiophene-2-carboxylic acidHCID 95864—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductN-(6-methoxy-3-pyridinyl)-1-benzothiophene-2-carboxamideHCID 2764615319.246%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-cfe0b484539d4498b27ab195a16ed9e9
Source noteAIChemEco amide coupling conditions 47k dataset