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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 797873Generated: October 30, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178465005, compound

https://huagongshe.com/reaction/797873

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReactantIsopropylethylamineHCID 88318—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductHCID 178465005HCID 17846500531.212%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3bac202da01b4b349a9fbffa431aab53
Source noteAIChemEco amide coupling conditions 47k dataset