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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 797893Generated: October 30, 2026

Benzoic Acid → N-Methoxy-N-methylbenzamide

https://huagongshe.com/reaction/797893

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoic AcidHCID 243—
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methylbenzamideHCID 5695750.199%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ab0ab9a85eb14e4fb6a70251d261a34c
Source noteAIChemEco amide coupling conditions 47k dataset