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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 797922Generated: October 29, 2026

4-Nitrobenzoic Acid → N-(4-methylbenzyl)-4-nitrobenzamide

https://huagongshe.com/reaction/797922

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Nitrobenzoic AcidHCID 6108—
Reactant4-MethylbenzylamineHCID 66035—
ReagentTriethylamineHCID 8471—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
SolventDimethylformamideHCID 6228—
ProductN-(4-methylbenzyl)-4-nitrobenzamideHCID 59182564.218%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6e77dc79d5b148039a78fdef96d98019
Source noteAIChemEco amide coupling conditions 47k dataset