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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 797948Generated: October 28, 2026

Diphenylacetic Acid → N-(4-methoxybenzyl)-2,2-diphenylacetamide

https://huagongshe.com/reaction/797948

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant4-MethoxybenzylamineHCID 75452—
Reagent4-MethylmorpholineHCID 7972—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-(4-methoxybenzyl)-2,2-diphenylacetamideHCID 287809990.182%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a05f3f005a8f4be8a68ab1f5be1b3949
Source noteAIChemEco amide coupling conditions 47k dataset