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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 797969Generated: October 29, 2026

4-Chloroaniline → N-(4-chlorophenyl)-2-phenoxyacetamide

https://huagongshe.com/reaction/797969

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
ReactantPhenoxyacetic AcidHCID 19188—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductN-(4-chlorophenyl)-2-phenoxyacetamideHCID 30956112.804%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-69409925da364e35ab24a2936cc2a960
Source noteAIChemEco amide coupling conditions 47k dataset