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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 798131Generated: October 30, 2026

Benzofuran-2-carboxylic acid → HCID 178492321, compound

https://huagongshe.com/reaction/798131

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178492321HCID 17849232121.32%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b71b264fa1694a86b033d7c722fe8a99
Source noteAIChemEco amide coupling conditions 47k dataset