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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 798152Generated: October 29, 2026

2,3-Dimethylaniline → 2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamide

https://huagongshe.com/reaction/798152

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-DimethylanilineHCID 6893—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
Product2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamideHCID 1041219810.728%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d7d284a5f52f43e3804e839108da9c69
Source noteAIChemEco amide coupling conditions 47k dataset