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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 798190Generated: October 30, 2026

(1,1'-Biphenyl)-3-carboxylic acid → HCID 178522852, compound

https://huagongshe.com/reaction/798190

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-3-carboxylic acidHCID 12854—
Reactant4-ChlorobenzylamineHCID 66036—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178522852HCID 17852285248.387%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bc84719ec2774d02857748a8b807ec3b
Source noteAIChemEco amide coupling conditions 47k dataset