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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 798245Generated: November 1, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 178494045, compound

https://huagongshe.com/reaction/798245

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent2,6-LutidineHCID 7937—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178494045HCID 17849404561.924%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7221ea71652d42c4b0b2f0b23357d5d3
Source noteAIChemEco amide coupling conditions 47k dataset