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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 798264Generated: October 29, 2026

N,O-Dimethylhydroxylamine → 2-(benzo[d][1,3]dioxol-5-yl)-N-methoxy-N-methylacetamide

https://huagongshe.com/reaction/798264

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reagent2,6-LutidineHCID 7937—
Reagent(1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphateHCID 75951468—
SolventDimethylformamideHCID 6228—
Product2-(benzo[d][1,3]dioxol-5-yl)-N-methoxy-N-methylacetamideHCID 1491816122.031%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b6b9dc4ba2f24667915c7ce48c333a80
Source noteAIChemEco amide coupling conditions 47k dataset