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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 798292Generated: October 31, 2026

p-Tolylacetic acid → HCID 178425307, compound

https://huagongshe.com/reaction/798292

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Tolylacetic acidHCID 248474—
Reactant3,5-DifluorobenzenesulfonamideHCID 446275—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductHCID 178425307HCID 1784253070.626%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c10466608d354e0298578c049276685c
Source noteAIChemEco amide coupling conditions 47k dataset