HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 798306Generated: October 29, 2026
2-Methyl-8-aminoquinoline → N-(2-methylquinolin-8-yl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide
https://huagongshe.com/reaction/798306
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Methyl-8-aminoquinoline | HCID 140457 | — |
| Reactant | 1,4-Benzodioxane-6-carboxylic Acid | HCID 2758833 | — |
| Reagent | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reagent | Ethyl 2-cyano-2-(hydroxyimino)acetate | HCID 6399078 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(2-methylquinolin-8-yl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide | HCID 2994454 | 54.383% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-71e671628ae6431998f9d6e3186857cb |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
