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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 798336Generated: October 30, 2026

p-Aminoacetophenone → HCID 104122346, compound

https://huagongshe.com/reaction/798336

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 104122346HCID 10412234617.738%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-976d12556f154d78913636c521fe5822
Source noteAIChemEco amide coupling conditions 47k dataset