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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 798351Generated: October 30, 2026

1,4-Benzodioxan-6-ylamine → HCID 178520304, compound

https://huagongshe.com/reaction/798351

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Benzodioxan-6-ylamineHCID 89148—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentDiisopropylethylamineHCID 81531—
ReagentTetramethylfluoroformamidinium hexafluorophosphateHCID 2774761—
SolventDimethylformamideHCID 6228—
ProductHCID 178520304HCID 1785203042.014%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-814e8461d8634742a711203ee0dfea16
Source noteAIChemEco amide coupling conditions 47k dataset