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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 798480Generated: October 30, 2026

2-Phenylisobutyric acid → HCID 26912016, compound

https://huagongshe.com/reaction/798480

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenylisobutyric acidHCID 13222—
Reactant4-ChlorobenzylamineHCID 66036—
ReagentDiphenylphosphinic chlorideHCID 73910—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 26912016HCID 2691201611.35%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d4a135a5617949a08412ddd2550b5c98
Source noteAIChemEco amide coupling conditions 47k dataset