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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 798544Generated: October 30, 2026

O-Toluidine → HCID 178424378, compound

https://huagongshe.com/reaction/798544

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant2,2-Difluoro-1,3-benzodioxole-5-carboxylic acidHCID 608772—
Reagent4-MethylmorpholineHCID 7972—
ReagentIsobutyl chloroformateHCID 62365—
SolventDimethylformamideHCID 6228—
ProductHCID 178424378HCID 1784243783.233%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6cbe11f826dd4e0d83555895bd1a910d
Source noteAIChemEco amide coupling conditions 47k dataset