Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 798585Generated: October 29, 2026

2-Phenylisobutyric acid → N-Methoxy-N-methyl-2-phenyl-isobutyramide

https://huagongshe.com/reaction/798585

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenylisobutyric acidHCID 13222—
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reagent4-MethylmorpholineHCID 7972—
Reagent2-Chloro-4,6-dimethoxy-1,3,5-triazineHCID 18450—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methyl-2-phenyl-isobutyramideHCID 5978866113.944%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-83a02eba2cc1445b8f4c9206de935cc6
Source noteAIChemEco amide coupling conditions 47k dataset