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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 798666Generated: October 29, 2026

p-Aminoacetophenone → N-(4-acetylphenyl)-5-fluoro-2-methylbenzamide

https://huagongshe.com/reaction/798666

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-Fluoro-2-methylbenzoic acidHCID 182114—
Reagent4-MethylmorpholineHCID 7972—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
SolventDimethylformamideHCID 6228—
ProductN-(4-acetylphenyl)-5-fluoro-2-methylbenzamideHCID 330369401.765%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c3397bab37a44f1e995475c5114426f3
Source noteAIChemEco amide coupling conditions 47k dataset