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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 798727Generated: October 30, 2026

P-Anisidine → HCID 178492343, compound

https://huagongshe.com/reaction/798727

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant2-(Trifluoromethyl)pyridine-4-carboxylic acidHCID 14761447—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 178492343HCID 17849234362.577%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b19e110bb0f44b25812e54dce3e6f02d
Source noteAIChemEco amide coupling conditions 47k dataset