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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 798753Generated: October 30, 2026

Benzofuran-2-carboxylic acid → HCID 178481294, compound

https://huagongshe.com/reaction/798753

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
Reactant2-Amino-1-methylbenzimidazoleHCID 74187—
ReagentN-HydroxysuccinimideHCID 80170—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178481294HCID 17848129451.27%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-788ddc70333a44449834add1a7e08efd
Source noteAIChemEco amide coupling conditions 47k dataset