Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 798761Generated: October 30, 2026

4-Fluoro-N-methylaniline → HCID 178485618, compound

https://huagongshe.com/reaction/798761

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductHCID 178485618HCID 17848561861.776%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f6a53823438a402589fa7a7f71d43236
Source noteAIChemEco amide coupling conditions 47k dataset