(3,5-Dichloropyridin-4-yl)methanol → [5-Chloro-4-(tetrahydro-pyran-2-yloxymethyl)-pyridin-3-yl]-methanol

HRID 798789Notes

Reaction equation

HRID 798789 reaction equation
[Cl:11][c:12]1[c:13]([CH2:20][O:21][CH:22]2[O:23][CH2:24][CH2:25][CH2:26][CH2:27]2)[c:14]([CH:18]=[O:19])[cH:15][n:16][cH:17]1.[Cl:1][c:2]1[cH:3][n:4][cH:5][c:6]([Cl:7])[c:8]1[CH2:9][OH:10]>>[Cl:11][c:12]1[c:13]([CH2:20][O:21][CH:22]2[O:23][CH2:24][CH2:25][CH2:26][CH2:27]2)[c:14]([CH2:18][OH:19])[cH:15][n:16][cH:17]1

Participants

3

Reactant 2

HCID 17855219(3,5-Dichloropyridin-4-yl)methanolHCID 441904745-Chloro-4-(tetrahydro-pyran-2-yloxymethyl)-pyridine-3-carbaldehyde

Product 1

HCID 44190475[5-Chloro-4-(tetrahydro-pyran-2-yloxymethyl)-pyridin-3-yl]-methanol

Sources & evidence

ORD record
ord-2fcc5a1d62024d0eb9dabe22c8bd425d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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