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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 798899Generated: October 30, 2026

Chloride → 2-(4-(3-Fluoro-4-trifluoromethoxyphenyl)-3,5-difluorophenyl)-5-pentylpyrimidine

https://huagongshe.com/reaction/798899

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
ReactantHexaneHCID 8058—
ReactantZinc(2+)HCID 32051—
Reactant4-Bromo-2-fluoro-1-(trifluoromethoxy)benzeneHCID 2782217—
Reactant2-(3,5-Difluorophenyl)-5-pentylpyrimidineHCID 18348270—
ReactantButyllithiumHCID 178418339—
Product2-(4-(3-Fluoro-4-trifluoromethoxyphenyl)-3,5-difluorophenyl)-5-pentylpyrimidineHCID 18348269—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-e660a9121c334fe08af23e66fcfaa27d
Source noteTest data from https://doi.org/10.1039/C8SC04228D