Ethanol → 2,4-Dihydro-4-(4-piperidinyl)-3H-1,2,4-triazol-3-one

HRID 799026Notes

Reaction equation

HRID 799026 reaction equation
[CH3:26][CH2:27][OH:28].[CH:20]1=[CH:25][CH2:24][CH:23]=[CH:22][CH2:21]1.[OH-:29].[OH-:31].[OH2:32].[Pd+2:30].[c:1]1([CH2:2][N:8]2[CH2:9][CH2:10][CH:11]([n:14]3[c:15](=[O:19])[nH:16][n:17][cH:18]3)[CH2:12][CH2:13]2)[cH:3][cH:4][cH:5][cH:6][cH:7]1>>[NH:8]1[CH2:9][CH2:10][CH:11]([n:14]2[c:15](=[O:19])[nH:16][n:17][cH:18]2)[CH2:12][CH2:13]1

Participants

7

Reactant 6

HCID 702EthanolHCID 961Hydroxide2×HCID 962WaterHCID 123431,4-CyclohexadieneHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 591757344-(1-Benzyl-4-piperidinyl)-3,4-dihydro-2H-1,2,4-triazole-3-one

Product 1

HCID 685022022,4-Dihydro-4-(4-piperidinyl)-3H-1,2,4-triazol-3-one

Sources & evidence

ORD record
ord-66502390f85c42f595bbc4573f97ee50
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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