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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 799089Generated: October 30, 2026

Dichloromethane → rac-(2R,3S,4R,5S)-5-(2-benzyloxycarbonyl-2-methyl-propyl)-3-(3-chloro-2-fluoro-phenyl)-4-(4-chloro-2-fluoro-phenyl)-4-cyano-pyrrolidine-2-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/799089

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
Reactanttert-ButanolHCID 6386—
ReactantTriethylamineHCID 8471—
Reactant1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
Reactant4-[(E)-tert-butoxycarbonylmethylimino]-2,2-dimethyl-butyric acid benzyl esterHCID 59249572—
ReactantC15H7Cl2F2NHCID 66665986—
Productrac-(2R,3S,4R,5S)-5-(2-benzyloxycarbonyl-2-methyl-propyl)-3-(3-chloro-2-fluoro-phenyl)-4-(4-chloro-2-fluoro-phenyl)-4-cyano-pyrrolidine-2-carboxylic acid tert-butyl esterHCID 67297241—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-39209309ac394646a3a03144f0660f9a
Source noteTest data from https://doi.org/10.1039/C8SC04228D