HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-carboxy-2-cyclopropylmethyl-6-[4-(methylthio)phenyl]-2H-pyridazin-3-one → 2-cyclopropylmethyl-4-hydroxymethyl-6-[4-(methylthio)-phenyl]-2H-pyridazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-carboxy-2-cyclopropylmethyl-6-[4-(methylthio)phenyl]-2H-pyridazin-3-one | HCID 21991424 | — |
| Reactant | 2-isobutyl-6-(2,4-difluorophenyl)-4-phthalimidomethyl-2H-pyridazin-3-one | HCID 21991587 | — |
| Product | 2-cyclopropylmethyl-4-hydroxymethyl-6-[4-(methylthio)-phenyl]-2H-pyridazin-3-one | HCID 21991592 | 22.6% |
Reaction Steps
Following the procedure of Example 1 (8), 4-carboxy-2-cyclopropylmethyl-6-[4-(methylthio)phenyl]-2H-pyridazin-3-one was reacted to yield the title compound as a pale yellow crystalline powder (yield: 22.6%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07087606B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-45b35999b6f84963bf5a02dbc2d4b406 |
| Source note | uspto-grants-2006_08 |