Water → tert-Butyl (3-chloro-6-hydroxy-1H-indol-1-yl)acetate

HRID 799133Notes

Reaction equation

HRID 799133 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][n:8]1[cH:9][c:10]([Cl:25])[c:11]2[cH:12][cH:13][c:14]([O:17][Si:18]([C:19]([CH3:20])([CH3:21])[CH3:22])([CH3:23])[CH3:24])[cH:15][c:16]12)=[O:26].[CH2:29]([N+:30]([CH2:31][CH2:32][CH2:33][CH3:34])([CH2:35][CH2:36][CH2:37][CH3:38])[CH2:39][CH2:40][CH2:41][CH3:42])[CH2:43][CH2:44][CH3:45].[F-:28].[OH2:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][n:8]1[cH:9][c:10]([Cl:25])[c:11]2[cH:12][cH:13][c:14]([OH:17])[cH:15][c:16]12)=[O:26]

Participants

5

Reactant 4

HCID 962WaterHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 69283059[6-(Tert-butyl-dimethyl-silanyloxy)-3-chloro-indol-1-yl]-acetic acid tert-butyl ester

Product 1

HCID 69283057tert-Butyl (3-chloro-6-hydroxy-1H-indol-1-yl)acetate

Sources & evidence

ORD record
ord-64c0182d7b6e46f4b8cd9a3d2540fced
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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