4-Bromopyrazole → 4-bromo-1-(2,2,2-trifluoroethyl)-1H-pyrazole

HRID 799312Notes

Reaction equation

HRID 799312 reaction equation
[Br:1][c:2]1[cH:3][n:4][nH:5][cH:6]1.[C:20](=[O:21])([O-:22])[O-:23].[CH2:26]1[O:27][CH2:28][CH2:29][O:30][CH2:31]1.[Cs+:24].[Cs+:25].[F:7][C:8]([F:9])([F:10])[S:11]([O:12][CH2:13][C:14]([F:15])([F:16])[F:17])(=[O:18])=[O:19]>>[Br:1][c:2]1[cH:3][n:4][n:5]([CH2:13][C:14]([F:15])([F:16])[F:17])[cH:6]1

Participants

6

Reactant 5

HCID 163754-BromopyrazoleHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 803662,2,2-Trifluoroethyl trifluoromethanesulfonateHCID 104967Cesium cation2×

Product 1

HCID 610302834-bromo-1-(2,2,2-trifluoroethyl)-1H-pyrazole

Sources & evidence

ORD record
ord-7fc3686fb8c54e9b94373f6589abde06
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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