Ethanol → 4-[5-chloro-2-(2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-8-ylamino)-pyrimidin-4-ylamino]-4'-cyano-5-fluoro-biphenyl-3-carboxylic acid methylamide

HRID 799561Notes

Reaction equation

[Br:1][c:2]1[cH:3][c:4]([F:33])[c:5]([NH:12][c:13]2[n:14][c:15]([NH:20][c:21]3[cH:22][cH:23][c:24]4[c:25]([cH:32]3)[NH:26][C:27](=[O:31])[CH2:28][CH2:29][CH2:30]4)[n:16][cH:17][c:18]2[Cl:19])[c:6]([C:7](=[O:8])[NH:9][CH3:10])[cH:11]1.[C:50](#[N:51])[c:52]1[cH:53][cH:54][c:55]([B:58]([OH:59])[OH:60])[cH:56][cH:57]1.[CH3:34][c:35]1[cH:36][cH:37][cH:38][cH:39][cH:40]1.[CH3:41][CH2:42][OH:43].[Na+:44].[Na+:45].[O-:46][C:47](=[O:48])[O-:49].[OH2:61].[cH:62]1[cH:63][cH:64][c:65]([P:66]([Pd:67]([P:68]([c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)([c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)[c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)([P:87]([c:88]2[cH:89][cH:90][cH:91][cH:92][cH:93]2)([c:94]2[cH:95][cH:96][cH:97][cH:98][cH:99]2)[c:100]2[cH:101][cH:102][cH:103][cH:104][cH:105]2)[P:106]([c:107]2[cH:108][cH:109][cH:110][cH:111][cH:112]2)([c:113]2[cH:114][cH:115][cH:116][cH:117][cH:118]2)[c:119]2[cH:120][cH:121][cH:122][cH:123][cH:124]2)([c:125]2[cH:126][cH:127][cH:128][cH:129][cH:130]2)[c:131]2[cH:132][cH:133][cH:134][cH:135][cH:136]2)[cH:137][cH:138]1>>[c:2]1(-[c:55]2[cH:54][cH:53][c:52]([C:50]#[N:51])[cH:57][cH:56]2)[cH:3][c:4]([F:33])[c:5]([NH:12][c:13]2[n:14][c:15]([NH:20][c:21]3[cH:22][cH:23][c:24]4[c:25]([cH:32]3)[NH:26][C:27](=[O:31])[CH2:28][CH2:29][CH2:30]4)[n:16][cH:17][c:18]2[Cl:19])[c:6]([C:7](=[O:8])[NH:9][CH3:10])[cH:11]1