2-Amino-5-m-tolyl-thiazole-4-carboxylic acid → N-[[2-[2-amino-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-2-azabicyclo[3.1.0]hexan-3-yl]methyl]-1-benzofuran-4-carboxamide

HRID 799698Notes

Reaction equation

HRID 799698 reaction equation
[CH:1]12[NH:2][CH:3]([CH2:7][NH:8][C:9](=[O:10])[c:11]3[cH:12][cH:13][cH:14][c:15]4[c:16]3[cH:17][cH:18][o:19]4)[CH2:4][CH:5]1[CH2:6]2.[NH2:20][c:21]1[s:22][c:23](-[c:29]2[cH:30][c:31]([CH3:35])[cH:32][cH:33][cH:34]2)[c:24]([C:26](=[O:27])[OH:28])[n:25]1>>[CH:1]12[N:2]([C:26]([c:24]3[c:23](-[c:29]4[cH:30][c:31]([CH3:35])[cH:32][cH:33][cH:34]4)[s:22][c:21]([NH2:20])[n:25]3)=[O:27])[CH:3]([CH2:7][NH:8][C:9](=[O:10])[c:11]3[cH:12][cH:13][cH:14][c:15]4[c:16]3[cH:17][cH:18][o:19]4)[CH2:4][CH:5]1[CH2:6]2

Participants

3

Reactant 2

HCID 532717422-Amino-5-m-tolyl-thiazole-4-carboxylic acidHCID 178522755HCID 178522755, compound

Product 1

HCID 178424764N-[[2-[2-amino-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-2-azabicyclo[3.1.0]hexan-3-yl]methyl]-1-benzofuran-4-carboxamide

Sources & evidence

ORD record
ord-4020ccf7df164a60b69ce0e83c686360
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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