Biphenyl-2-boronic acid → 2-biphenyl-2-yl-5-(2,6-difluorophenyl)-6H-pyrido[1,2-b]pyridazin-6-one
Reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]2[n:6]([n:7]1)[cH:8][cH:9][c:10](=[O:20])[c:11]2-[c:12]1[c:13]([F:19])[cH:14][cH:15][cH:16][c:17]1[F:18].[c:21]1(-[c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[c:22]([B:27]([OH:28])[OH:29])[cH:23][cH:24][cH:25][cH:26]1>>[c:2]1(-[c:22]2[c:21](-[c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[cH:26][cH:25][cH:24][cH:23]2)[cH:3][cH:4][c:5]2[n:6]([n:7]1)[cH:8][cH:9][c:10](=[O:20])[c:11]2-[c:12]1[c:13]([F:19])[cH:14][cH:15][cH:16][c:17]1[F:18]Participants
3
Sources & evidence
- ORD record
- ord-c08479939b4847ddb5c58d145da6b16e
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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