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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 799791Generated: October 30, 2026

Toluene → [3-(2,2-Difluoro-2-phenyl-ethylamino)-6-methyl-2-oxo-2H-pyrazin-1-yl]-acetic acid ethyl ester

https://huagongshe.com/reaction/799791

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantEthyl AcetateHCID 8857—
ReactantEthyl 2-(3-bromo-6-methyl-2-oxopyrazin-1(2H)-yl)acetateHCID 1514288—
Reactant2,2-Difluoro-2-phenylethylamineHCID 12635529—
Product[3-(2,2-Difluoro-2-phenyl-ethylamino)-6-methyl-2-oxo-2H-pyrazin-1-yl]-acetic acid ethyl esterHCID 22179412—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-8602bf836d9649b896a04782c6ebda30
Source noteTest data from https://doi.org/10.1039/C8SC04228D