2-Amino-5-m-tolyl-thiazole-4-carboxylic acid → N-[[2-[2-amino-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-2-azabicyclo[3.1.0]hexan-3-yl]methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxamide

HRID 799849Notes

Reaction equation

HRID 799849 reaction equation
[CH:1]12[NH:2][CH:3]([CH2:7][NH:8][C:9](=[O:10])[c:11]3[cH:12][cH:13][cH:14][c:15]4[c:20]3[O:19][CH2:18][CH2:17][O:16]4)[CH2:4][CH:5]1[CH2:6]2.[NH2:21][c:22]1[s:23][c:24](-[c:30]2[cH:31][c:32]([CH3:36])[cH:33][cH:34][cH:35]2)[c:25]([C:27](=[O:28])[OH:29])[n:26]1>>[CH:1]12[N:2]([C:27]([c:25]3[c:24](-[c:30]4[cH:31][c:32]([CH3:36])[cH:33][cH:34][cH:35]4)[s:23][c:22]([NH2:21])[n:26]3)=[O:28])[CH:3]([CH2:7][NH:8][C:9](=[O:10])[c:11]3[cH:12][cH:13][cH:14][c:15]4[c:20]3[O:19][CH2:18][CH2:17][O:16]4)[CH2:4][CH:5]1[CH2:6]2

Participants

3

Reactant 2

HCID 532717422-Amino-5-m-tolyl-thiazole-4-carboxylic acidHCID 178522754HCID 178522754, compound

Product 1

HCID 178424763N-[[2-[2-amino-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-2-azabicyclo[3.1.0]hexan-3-yl]methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxamide

Sources & evidence

ORD record
ord-ae9c831caf5c4068b3f825411845e237
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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