Methanol → N~1~-(1-Benzylpiperidin-4-yl)-N~2~-phenylethane-1,2-diamine

HRID 799907Notes

Reaction equation

HRID 799907 reaction equation
[C:25]([BH3-:26])#[N:27].[CH2:11]([c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1)[N:18]1[CH2:19][CH2:20][C:21](=[O:24])[CH2:22][CH2:23]1.[CH3:29][OH:30].[Na+:28].[c:1]1([NH:7][CH2:8][CH2:9][NH2:10])[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([NH:7][CH2:8][CH2:9][NH:10][CH:21]2[CH2:20][CH2:19][N:18]([CH2:11][c:12]3[cH:13][cH:14][cH:15][cH:16][cH:17]3)[CH2:23][CH2:22]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

6

Reactant 5

HCID 887MethanolHCID 923Sodium ionHCID 192201-Benzyl-4-piperidoneHCID 742701,2-Ethanediamine, N1-phenyl-HCID 498716Cyano-borohydride

Product 1

HCID 20540168N~1~-(1-Benzylpiperidin-4-yl)-N~2~-phenylethane-1,2-diamine

Sources & evidence

ORD record
ord-ee505fe319d2486d96e4bf82abf9657d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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