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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 8000Generated: October 28, 2026

tert-Butyl piperazine-1-carboxylate → HCID 21991627, compound

https://huagongshe.com/reaction/8000

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl piperazine-1-carboxylateHCID 143452—
Reactant2-isobutyl-4-methanesulfonyloxymethyl-6-[4-(methylsulfonyl)phenyl]-2H-pyridazin-3-oneHCID 21991524—
Reactant4-(4-tert-butoxycarbonyl-1-piperazinyl)-methyl-6-(3-fluoro-4-methylphenyl)-2-isobutyl-2H-pyridazin-3-oneHCID 67214099—
ProductHCID 21991627HCID 2199162775.9%

Reaction Steps

Following the procedure of Example 1 (10), 2-isobutyl-4-methanesulfonyloxymethyl-6-[4-(methylsulfonyl)phenyl]-2H-pyridazin-3-one and tert-butyl 1-piperazinecarboxylate were reacted to yield the title compound as a yellow oil (yield: 75.9%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07087606B2
Source datasetuspto-grants-2006_08
ORD IDord-b331aaf73d044d758947cdf38450e89d
Source noteuspto-grants-2006_08