1-(4-Amino-2-methylquinolin-3-yl)ethanone → 1-(4-(4-Bromo-2-fluorobenzylamino)-2-methylquinolin-3-yl)ethanone
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:7][c:8]2[c:9]([C:19]([CH3:20])=[O:21])[c:10]([CH3:18])[n:11][c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]23)[cH:22][cH:23]1.[Br:39][c:40]1[cH:41][cH:42][c:43]([CH2:44][Br:45])[c:46]([F:48])[cH:47]1.[NH2:24][c:25]1[c:26]2[c:27]([cH:28][cH:29][cH:30][cH:31]2)[n:32][c:33]([CH3:34])[c:35]1[C:36](=[O:37])[CH3:38]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:7][c:8]2[c:9]([C:19]([CH3:20])=[O:21])[c:10]([CH3:18])[n:11][c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]23)[c:22]([F:48])[cH:23]1Participants
4
Sources & evidence
- ORD record
- ord-31a3ee515ae04499b0e8c81a73e7b625
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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