Methanol → 5-amino-2-tert-butyl-1H-indole-7-carbonitrile

HRID 800108Notes

Reaction equation

HRID 800108 reaction equation

[BH4-:19].[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[nH:6][c:7]2[c:8]([C:17]#[N:18])[cH:9][c:10]([N+:14]([O-:15])=[O:16])[cH:11][c:12]2[cH:13]1.[CH3:21][OH:22].[Na+:20]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[nH:6][c:7]2[c:8]([C:17]#[N:18])[cH:9][c:10]([NH2:14])[cH:11][c:12]2[cH:13]1

Participants

5

Reactant 4

HCID 887Methanol

HCID 923Sodium ion

HCID 28123Borohydride

HCID 534211842-Tert-butyl-5-nitro-1H-indole-7-carbonitrile

Product 1

HCID 591292165-amino-2-tert-butyl-1H-indole-7-carbonitrile

Sources & evidence

ORD record: ord-ba40589d649a410ab1d1bff219f6c966
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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