N-(5,5-Dimethyl-8-nitro-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl)-acetamide → 2-[2-(3-Acetylamino-5,5-dimethyl-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-8-ylamino)-5-chloro-pyrimidin-4-ylamino]-3-fluoro-N-methyl-benzamide
Reaction equation
[CH3:1][C:2]1([CH3:21])[CH2:3][CH:4]([NH:17][C:18]([CH3:19])=[O:20])[C:5](=[O:16])[NH:6][c:7]2[c:8]1[cH:9][cH:10][c:11]([N+:13]([O-:14])=[O:15])[cH:12]2.[Cl:22][c:23]1[n:24][cH:25][c:26]([Cl:41])[c:27]([NH:29][c:30]2[c:31]([C:32](=[O:33])[NH:34][CH3:35])[cH:36][cH:37][cH:38][c:39]2[F:40])[n:28]1>>[CH3:1][C:2]1([CH3:21])[CH2:3][CH:4]([NH:17][C:18]([CH3:19])=[O:20])[C:5](=[O:16])[NH:6][c:7]2[c:8]1[cH:9][cH:10][c:11]([NH:13][c:23]1[n:24][cH:25][c:26]([Cl:41])[c:27]([NH:29][c:30]3[c:31]([C:32](=[O:33])[NH:34][CH3:35])[cH:36][cH:37][cH:38][c:39]3[F:40])[n:28]1)[cH:12]2Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-fa6cb5e70b7c4cff8b499ddc3ee3d453
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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