tert-Butyl piperazine-1-carboxylate → Tert-butyl 4-(3-chloro-5-(methoxy(methyl)carbamoyl)pyridin-2-yl)piperazine-1-carboxylate

HRID 800471Notes

Reaction equation

HRID 800471 reaction equation
[C:15]([CH3:16])([CH3:17])([CH3:18])[O:19][C:20](=[O:21])[N:22]1[CH2:23][CH2:24][NH:25][CH2:26][CH2:27]1.[Cl:1][c:2]1[c:3]([Cl:14])[n:4][cH:5][c:6]([C:7](=[O:8])[N:9]([CH3:10])[O:11][CH3:12])[cH:13]1>>[Cl:1][c:2]1[c:3]([N:25]2[CH2:24][CH2:23][N:22]([C:20]([O:19][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:21])[CH2:27][CH2:26]2)[n:4][cH:5][c:6]([C:7](=[O:8])[N:9]([CH3:10])[O:11][CH3:12])[cH:13]1

Participants

3

Reactant 2

HCID 143452tert-Butyl piperazine-1-carboxylateHCID 115069195,6-dichloro-N-methoxy-N-methylpyridine-3-carboxamide

Product 1

HCID 11646699Tert-butyl 4-(3-chloro-5-(methoxy(methyl)carbamoyl)pyridin-2-yl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-4e99ee278a014b2ebdddec3c24911e49
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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