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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 800518Generated: November 1, 2026

Tetrahydrofuran → N-(2-{[5-chloro-3-(4-chloro-3-trifluoromethyl-benzenesulfonylamino)-pyridin-2-yl]-hydroxy-methyl}-3-methoxy-phenyl)-2,2-dimethyl-propionamide

https://huagongshe.com/reaction/800518

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantN-(3-methoxyphenyl)pivalamideHCID 546358—
Reactant4-chloro-N-(5-chloro-2-formyl-pyridin-3-yi)-3-trifluoromethyl-benzenesulfonamideHCID 57942491—
ReactantButyllithiumHCID 178418339—
ProductN-(2-{[5-chloro-3-(4-chloro-3-trifluoromethyl-benzenesulfonylamino)-pyridin-2-yl]-hydroxy-methyl}-3-methoxy-phenyl)-2,2-dimethyl-propionamideHCID 57942304—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-5a11c6d14a2f4205b98548fbc91d90d2
Source noteTest data from https://doi.org/10.1039/C8SC04228D