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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 800633Generated: October 25, 2026

Dimethylformamide → 4-[5-Bromo-6-(2-methyl-2-morpholin-4-yl-propylamino)-pyridine-3-sulfonyl]-5-methylsulfanyl-thiophene-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/800633

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTetrahydrofuranHCID 8028—
ReactantDiisopropylethylamineHCID 81531—
Reactant2-Methyl-2-(morpholin-4-yl)propan-1-amineHCID 1989641—
Reactant4-(5-Bromo-6-chloro-pyridine-3-sulfonyl)-5-methylsulfanyl-thiophene-2-carboxylic acid methyl esterHCID 21057179—
Product4-[5-Bromo-6-(2-methyl-2-morpholin-4-yl-propylamino)-pyridine-3-sulfonyl]-5-methylsulfanyl-thiophene-2-carboxylic acid methyl esterHCID 69586470—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-ccc8b65ae53c4208bccca4d7e5296c08
Source noteTest data from https://doi.org/10.1039/C8SC04228D