4-Chlorophenylboronic acid → 4-(4-Chlorophenyl)-N-(5-(cyclopropylcarbamoyl)-2-methylphenyl)-3-methylthiophene-2-carboxamide
Reaction equation
[Br:1][c:2]1[c:3]([CH3:23])[c:4]([C:7](=[O:8])[NH:9][c:10]2[c:11]([CH3:22])[cH:12][cH:13][c:14]([C:16]([NH:17][CH:18]3[CH2:19][CH2:20]3)=[O:21])[cH:15]2)[s:5][cH:6]1.[Cl:24][c:25]1[cH:26][cH:27][c:28]([B:31]([OH:32])[OH:33])[cH:29][cH:30]1>>[c:2]1(-[c:28]2[cH:27][cH:26][c:25]([Cl:24])[cH:30][cH:29]2)[c:3]([CH3:23])[c:4]([C:7](=[O:8])[NH:9][c:10]2[c:11]([CH3:22])[cH:12][cH:13][c:14]([C:16]([NH:17][CH:18]3[CH2:19][CH2:20]3)=[O:21])[cH:15]2)[s:5][cH:6]1Participants
3
Sources & evidence
- ORD record
- ord-592faa6efc924ed2a462287ae14d285f
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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