5-Bromo-4-methylthiophene-2-carbonitrile → 4-Methyl-5-(2,4,4-trimethyl-1,4-dihydro-2H-3,1-benzoxazin-6-yl)thiophene-2-carbonitrile

HRID 800810Notes

Reaction equation

HRID 800810 reaction equation
[Br:15][c:16]1[c:17]([CH3:23])[cH:18][c:19]([C:21]#[N:22])[s:20]1.[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:14]1)[C:7]([CH3:12])([CH3:13])[O:8][CH:9]([CH3:11])[NH:10]2>>[c:2]1(-[c:16]2[c:17]([CH3:23])[cH:18][c:19]([C:21]#[N:22])[s:20]2)[cH:3][cH:4][c:5]2[c:6]([cH:14]1)[C:7]([CH3:12])([CH3:13])[O:8][CH:9]([CH3:11])[NH:10]2

Participants

3

Reactant 2

HCID 219862345-Bromo-4-methylthiophene-2-carbonitrileHCID 234355746-Bromo-2,4,4-trimethyl-2,4-dihydro-1H-benzo[D][1,3]oxazine

Product 1

HCID 234355894-Methyl-5-(2,4,4-trimethyl-1,4-dihydro-2H-3,1-benzoxazin-6-yl)thiophene-2-carbonitrile

Sources & evidence

ORD record
ord-708f3b26f9b143818bfabd9f058dfd03
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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