HCID 23146280, compound → (RS)-1-[2-(5-Cyano-benzofuran-2-ylmethyl)-piperidin-1-yl]-1-[5-(4-fluoro-phenyl)-2-methyl-thiazol-4-yl]-methanone

HRID 800998Notes

Reaction equation

HRID 800998 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:7][c:8]([CH2:10][CH:11]3[N:12]([C:17](=[O:18])[c:19]4[n:20][c:21]([CH3:31])[s:22][c:23]4-[c:24]4[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]4)[CH2:13][CH2:14][CH2:15][CH2:16]3)[o:9]2)[cH:32]1.[Cu:33][C:34]#[N:35]>>[c:2]1([C:34]#[N:35])[cH:3][cH:4][c:5]2[c:6]([cH:7][c:8]([CH2:10][CH:11]3[N:12]([C:17](=[O:18])[c:19]4[n:20][c:21]([CH3:31])[s:22][c:23]4-[c:24]4[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]4)[CH2:13][CH2:14][CH2:15][CH2:16]3)[o:9]2)[cH:32]1

Participants

3

Reactant 2

HCID 23146280HCID 23146280, compoundHCID 178418546HCID 178418546, compound

Product 1

HCID 23146247(RS)-1-[2-(5-Cyano-benzofuran-2-ylmethyl)-piperidin-1-yl]-1-[5-(4-fluoro-phenyl)-2-methyl-thiazol-4-yl]-methanone

Sources & evidence

ORD record
ord-b585aa956b2e467485c6b8859a69aa28
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…