6-(2,4-difluorophenyl)-2-isobutyl-4-methanesulfonyloxym ethyl-2H-pyridazin-3-one → 4-carboxy-2-(4-fluorobenzyl)-6-(3-fluoro-4-methoxyphenyl)-2H-pyridazin-3-one

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	6-(2,4-difluorophenyl)-2-isobutyl-4-methanesulfonyloxym ethyl-2H-pyridazin-3-one	HCID 21991416	—
Edukt	2-(4-fluorobenzyl)-6-(3-fluoro-4-methoxyphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one	HCID 21991566	—
Produkt	4-carboxy-2-(4-fluorobenzyl)-6-(3-fluoro-4-methoxyphenyl)-2H-pyridazin-3-one	HCID 21991407	97,7%

Reaktionsschritte

Following the procedure of Example 1 (7), 2-(4-fluorobenzyl)-6-(3-fluoro-4-methoxyphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one was reacted to yield the title compound as a yellow powder (yield: 97.7%).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07087606B2
Quelldatensatz	uspto-grants-2006_08
ORD ID	ord-b14b2f59787d4ae3b3b8712a938b923e
Quellennotiz	uspto-grants-2006_08