(4-(Morpholin-4-yl)phenyl)boronic acid → Tert-butyl 4-((2-(cis-4-methylcyclohexylamino)-5-(4-morpholinophenyl)pyrimidin-4-yloxy)methyl)piperidine-1-carboxylate
Reaction equation
[CH3:1][CH:2]1[CH2:3][CH2:4][CH:5]([NH:8][c:9]2[n:10][cH:11][c:12]([Br:30])[c:13]([O:15][CH2:16][CH:17]3[CH2:18][CH2:19][N:20]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:21][CH2:22]3)[n:14]2)[CH2:6][CH2:7]1.[O:31]1[CH2:32][CH2:33][N:34]([c:37]2[cH:38][cH:39][c:40]([B:43]([OH:44])[OH:45])[cH:41][cH:42]2)[CH2:35][CH2:36]1>>[CH3:1][CH:2]1[CH2:3][CH2:4][CH:5]([NH:8][c:9]2[n:10][cH:11][c:12](-[c:40]3[cH:39][cH:38][c:37]([N:34]4[CH2:33][CH2:32][O:31][CH2:36][CH2:35]4)[cH:42][cH:41]3)[c:13]([O:15][CH2:16][CH:17]3[CH2:18][CH2:19][N:20]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:21][CH2:22]3)[n:14]2)[CH2:6][CH2:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-6afafc56cf2b46e1b409c8ea139befb8
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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